Ophthalmology in China

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The application of macular ganglion cell-inner plexiform layer thickness measured by spectral-domain optical coherence tomography in early glaucoma diagnosis 

LIU Xing, XU Xiao-yu.   

  1. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
  • Received:2016-01-11 Online:2016-01-25 Published:2016-01-28

Abstract:

Macular ganglion cells-inner plexiform layer (GCIPL) thickness detected by SD-OCT may be a better method than peripapillary retinal nerve fiber layer (RNFL) thickness and macular ganglion cell complex (GCC) for earlier diagnosis of glaucomatous damage. GCIPL in  superonasal sector is the thickest while GCIPL in inferior sector is the thinnest in Asian population. Age and the axial length are important impact factors of GCIPL thickness. GCIPL thickness has similar glaucoma distinguishing performance with RNFL thickness. Mutual integration of visual field testing, GCIPL thickness, RNFL thickness and optic disc parameters is the key to enable early detection of glaucoma. (Ophthalmol CHN, 2016, 25: 1-5)

Key words: spectral-domain optical coherence tomography, glaucoma, early diagnosis, ganglion cell-inner plexiform layer